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Updated: Jul 13, 2026

Generation and Quantitative Analysis of Pulsed Low Frequency Ultrasound to Determine the Sonic Sensitivity of Untreated and Treated Neoplastic Cells
Published on: July 22, 2015
High-intensity focused ultrasound (HIFU) for prostate cancer
Francois-Joseph Murat1, Laura Poissonnier, Gilles Pasticier
1Urology and Transplantation Department, Edouard Herriot Hospital, 69347 Lyon Cedex 03, France. gfj-murat@club-internet.fr
Background:
The growing interest in high-intensity focused ultrasound (HIFU) is mainly due to its potential applications as a minimally invasive therapy. HIFU has been assessed for its role in the treatment of localized prostate cancer in patients who otherwise would not have benefited from surgery and in local recurrences after radiation failure.
Methods:
Relevant information on HIFU treatment was identified through a MEDLINE search using specified terms. Papers that presented original outcomes were included in the present review.
Results:
High biochemical efficacy, excellent tumor local control and favorable mid-term oncological data with a low morbidity rate have been proven in many series of patients.
Conclusions:
Although HIFU is a recent and emerging technology, it has been well studied and developed to a point that HIFU will undoubtedly be an effective alternative to radiation therapy.
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