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Robust, routine haematology reference ranges for healthy adults
L Wakeman1, S Al-Ismail, A Benton
1Haematology Department, Singleton Hospital, Swansea, UK. lisa.wakeman@swansea-tr.wales.nhs.uk
International Journal of Laboratory Hematology
|July 10, 2007
Summary
This study establishes reliable laboratory reference ranges for haematology, coagulation, and haematinic parameters in healthy adults. These robust ranges are crucial for accurate clinical evaluation and patient monitoring.
Area of Science:
- Clinical Laboratory Science
- Hematology
- Coagulation Studies
Background:
- Accurate laboratory reference ranges are fundamental for effective clinical decision-making.
- Establishing reliable ranges ensures proper interpretation of patient results.
- Existing ranges may not reflect current population or analytical standards.
Purpose of the Study:
- To establish robust and reliable laboratory reference ranges for key haematology, coagulation, and haematinic parameters.
- To provide updated reference values for healthy adult populations.
- To validate these ranges using modern analytical instrumentation.
Main Methods:
- Blood samples were collected from 250 healthy adult laboratory personnel.
- Routine haematology, coagulation, and haematinic parameters were analyzed.
- Analysis was performed using Sysmex XE 2100, CA 1500, and Beckman-Coulter Access analyzers.
Main Results:
- Established comprehensive reference ranges for haematology parameters.
- Defined reliable reference ranges for coagulation tests.
- Provided validated reference ranges for haematinic markers.
- Data generated from a healthy adult cohort.
Conclusions:
- The study successfully established robust reference ranges for haematology, coagulation, and haematinic parameters.
- These validated ranges are essential for accurate clinical evaluation and monitoring.
- The findings support the use of modern analyzers for generating reliable laboratory standards.
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