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Changes in total body water during spaceflight.

C S Leach1, L D Inners, J B Charles

  • 1Medical Sciences Division, NASA Johnson Space Center, Houston, Texas 77058.

Journal of Clinical Pharmacology
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

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Astronauts experience a 3.4% decrease in total body water (TBW) within days of spaceflight. This fluid shift in microgravity may be linked to reduced water intake and space motion sickness (SMS).

Area of Science:

  • Space physiology
  • Human physiology in microgravity
  • Fluid dynamics

Background:

  • Measuring body fluid compartments directly in space is challenging.
  • Understanding fluid shifts is crucial for astronaut health during space missions.

Purpose of the Study:

  • To directly measure a body fluid compartment during spaceflight.
  • To quantify changes in total body water (TBW) in astronauts exposed to microgravity.

Main Methods:

  • Direct measurement of a body fluid compartment was performed.
  • Data collected from five crew members aboard the Space Shuttle.

Main Results:

  • Total body water (TBW) decreased by 3.4% after 1-3 days in microgravity.
Keywords:
NASA Center JSCNASA Discipline Number 00-00NASA Discipline Number 18-10NASA Discipline Regulatory PhysiologyNASA Experiment Number DSO460NASA Program FlightNASA Program Space Physiology and Countermeasures

Related Experiment Videos

  • Some individuals showed TBW reduction within 24 hours.
  • Nausea associated with space motion sickness (SMS) may contribute to decreased water intake and TBW loss.

    • Conclusions:

    • Microgravity exposure leads to a significant decrease in astronaut total body water.
    • Individual responses to microgravity vary, with some experiencing rapid fluid shifts.
    • Space motion sickness and reduced hydration are potential contributing factors to observed fluid loss.