Related Experiment Videos
Aspirin and bleeding in dentistry: an update and recommendations
Michael T Brennan1, Richard L Wynn, Craig S Miller
1Oral Medicine Residency Director, Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC, USA.
Low-dose aspirin is recommended for cardiovascular prevention. Recent evidence suggests continuing aspirin during dental procedures minimizes thrombotic risks, outweighing bleeding concerns.
Area of Science:
- Cardiovascular Medicine
- Dental Surgery
- Pharmacology
Background:
- Aspirin is widely used for cardiovascular thrombotic event prevention.
- Its antiplatelet effect raises concerns about bleeding after dental extractions.
- Discontinuing aspirin may pose thrombotic risks.
Purpose of the Study:
- To review evidence on thrombotic risks of discontinuing aspirin.
- To present updated recommendations for aspirin use during dental procedures.
Main Methods:
- Review of recent scientific literature.
- Analysis of thrombotic risks versus bleeding risks.
- Formulation of clinical recommendations.
Main Results:
- Discontinuing aspirin increases thrombotic event risk in high-risk patients.
- The risk of thrombosis from aspirin cessation often exceeds bleeding risk from dental procedures.
- Continuing low-dose aspirin may be safe and beneficial.
Conclusions:
- Patients at risk for cardiovascular thrombotic events should continue low-dose aspirin during invasive dental procedures.
- Updated guidelines support continuing aspirin to prevent thrombotic events.
- Balancing bleeding and thrombotic risks favors aspirin continuation in select patients.
Related Concept Videos
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Tonsillitis II: Management
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management