Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Giant basal cell carcinoma.

Antonio Fresini, Luigi Rossiello, Beatrice Ulloa Severino

    Skinmed
    |July 10, 2007
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Deprescription of benzodiazepines and its management according to an overlapping strategy with a low-dose multicomponent medication: a Delphi consensus.

    Panminerva medica·2025
    Same author

    Cutaneous Leiomyoma Mimicking Molluscum Contagiosum.

    Dermatology practical & conceptual·2024
    Same author

    Colorectal screening following appendectomy in adult patients: a systematic review.

    Annals of coloproctology·2024
    Same author

    Overlapping approach Proton Pump Inhibitors/Nux vomica-Heel as new intervention for gastro-esophageal reflux management: Delphi consensus study.

    World journal of gastroenterology·2024
    Same author

    Systematic intraoperative cholangiography during elective laparoscopic cholecystectomy: Is it a justifiable practice?

    Annals of hepato-biliary-pancreatic surgery·2023
    Same author

    Dermatologic Manifestations of Thymoma-associated Multiorgan Autoimmunity (TAMA) Syndrome: Cutaneous Signs of an Immune Dysregulation.

    Dermatology practical & conceptual·2022

    A large, aggressive basal cell carcinoma (BCC) with an adenoid subtype was diagnosed in a 72-year-old man. Due to comorbidities, radiation therapy was chosen over surgery for this extensive skin cancer.

    Area of Science:

    • Dermatology
    • Oncology
    • Pathology

    Background:

    • Presents a rare case of a large, aggressive basal cell carcinoma (BCC) with an adenoid subtype in a 72-year-old male patient.
    • The cutaneous tumor exhibited significant growth over seven years, presenting as a vegetating, ulcerated mass with associated anemia, hyperuricemia, and hypercholesterolemia.

    Observation:

    • Physical examination revealed a 30 x 20 cm tumor with features of inflammation and impaired lymphatic flow.
    • Histopathological analysis demonstrated an adenoid pattern with basaloid cells exhibiting atypia, pleomorphism, and hyperchromatism, indicative of invasive BCC.
    • Magnetic resonance imaging confirmed subcutaneous thickening and partial neoplastic infiltration of the muscle fascia.

    Findings:

    • The diagnosis was confirmed as basal cell carcinoma, adenoid subtype, a rare and aggressive variant.

    Related Experiment Videos

  • No evidence of metastasis was detected via computed tomography scan.
  • The patient's comorbidities, including anticoagulant use and unstable cardiac/renal function, precluded immediate surgical intervention.

    • Implications:

    • Radiation therapy was selected as the primary treatment modality due to the patient's clinical profile and tumor characteristics.
    • This case highlights the importance of thorough histopathological evaluation for diagnosing rare and aggressive skin cancers.
    • Management strategies for extensive BCC must consider patient comorbidities and potential treatment risks.