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Sacral nerve neuromodulation in patients with underlying neurologic disease
Patricia A Wallace1, Felicia L Lane, Karen L Noblett
1Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, University of California, Irvine, School of Medicine, Orange, CA 92868, USA. pwallace@uci.edu
American Journal of Obstetrics and Gynecology
|July 10, 2007
Summary
Sacral nerve neuromodulation (SNS) effectively treats lower urinary tract dysfunction in patients with neurologic conditions. This therapy significantly reduces incontinence and nocturia, improving quality of life.
Area of Science:
- Neurology
- Urology
Background:
- Lower urinary tract dysfunction (LUTD) is common in patients with neurologic diseases.
- Sacral nerve neuromodulation (SNS) is a recognized treatment for LUTD.
Purpose of the Study:
- To evaluate the efficacy of SNS in patients with LUTD secondary to underlying neurologic dysfunction.
Main Methods:
- Retrospective case series of 33 patients with neurologic disease and LUTD.
- Patients underwent sacral nerve stimulation (InterStim).
- Outcomes assessed via pre- and postoperative voiding diaries; success defined as >50% improvement.
Main Results:
- 85% of patients (28/33) received implants.
- Significant reductions observed: 68% fewer incontinence episodes, 43% fewer voids, 70% less nocturia, 58% reduction in self-catheterization.
- High patient satisfaction reported at 93%.
Conclusions:
- Sacral nerve neuromodulation demonstrates effectiveness in managing LUTD in patients with underlying neurologic disorders.
- SNS offers a viable therapeutic option for improving bladder function and quality of life in this patient population.
