Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abdominal wall repair using human acellular dermis.

Charles F Bellows1, Daniel Albo, David H Berger

  • 1Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Michael E. DeBakey Veterans Affairs Hospital, m/c 112, 2002 Holcombe Blvd., Houston, TX 77030, USA. cbellows@bcm.tmc.edu

American Journal of Surgery
|July 10, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High Prices, Low Outcomes-The Truth Behind Hospital Markups.

JAMA surgery·2025
Same author

Turning Tides: Evolving Comorbidity Profiles, Demographic Shift, and the Unexpected Rise of Major Lower Extremity Amputations.

Annals of surgery·2025
Same author

Intraoperative fluid rate and postoperative complications for pancreatoduodenectomy.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2025
Same author

REBOA Use and Complications in Geriatric Trauma Patients: Insights From a Multicenter Database.

The Journal of surgical research·2025
Same author

Multidisciplinary Amputation Prevention at the DeBakey VA Hospital: Our First Decade.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2025
Same author

Variation in Long-Term Postoperative Mortality Risk by Race/Ethnicity After Major Non-cardiac Surgeries in the Veterans Health Administration.

Journal of racial and ethnic health disparities·2024
Same journal

Women with firearm injuries: A multicenter mixed-methods study.

American journal of surgery·2026
Same journal

SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

American journal of surgery·2026
Same journal

Using Dr. Google and AI to stay informed.

American journal of surgery·2026
Same journal

Revealing the sex divide: Primary hyperparathyroidism across the American population.

American journal of surgery·2026
Same journal

Pressure points: A pilot study using the NASA-TLX tool to measure the intensity of Acute care surgery work.

American journal of surgery·2026
Same journal

Raised to run faster, not to heal moral injury and the surgeon's capacity to lead.

American journal of surgery·2026
See all related articles

Human acellular dermal graft is a safe option for abdominal wall reconstruction in contaminated surgical wounds. This study evaluated its use in 20 patients, noting complications and hernia recurrence rates.

Area of Science:

  • Surgical Innovation
  • Biomaterials Science
  • Wound Healing

Background:

  • Abdominal wall reconstruction in contaminated fields presents challenges, often contraindicating synthetic mesh due to infection risks.
  • Human acellular dermal graft (HADD) offers a potential alternative for complex hernia repairs.
  • This study investigates the safety and efficacy of HADD in challenging surgical scenarios.

Purpose of the Study:

  • To evaluate the safety and efficacy of human acellular dermal graft for abdominal wall reconstruction.
  • To assess complication rates and hernia recurrence after HADD implantation in contaminated wounds.

Main Methods:

  • Retrospective review of 20 patients undergoing abdominal wall reconstruction with HADD.
  • Data collection included patient demographics, perioperative complications, and hernia recurrence.

Related Experiment Videos

  • Follow-up duration averaged 9.4 months.

    • Main Results:

    • 15 perioperative complications occurred in 11 patients, including graft dehiscence, evisceration, bleeding, and bacterial graft infections.
    • Patients with comorbidities (heart disease, ASA class 4) and contaminated wounds had higher complication rates.
    • Six hernia recurrences were observed during the follow-up period.

    Conclusions:

    • Human acellular dermal graft demonstrates safety for abdominal wall reconstruction in contaminated surgical settings.
    • While complications can occur, HADD provides a viable option where synthetic meshes are contraindicated.
    • Further research may optimize patient selection and surgical techniques to minimize HADD-related complications.