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Updated: Jul 13, 2026

A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
Published on: March 26, 2019
[Relationship between P300 and intelligence quotient in severe head injury patients]
Yu-Qing Liu1, Ling-Li Zhang, Xiao-Hong Zhao
1Department of Forensic Medicine, Tongii Medical College of Huazhong University of Science and Technology, Wuhan 430030, China.
Objective:
To explore the change of brain cognition function in severe head injury and the correlation between P300 in event-related potential (ERP) and intelligence quotient (IQ).
Methods:
Auditory P300 was measured and intelligence quotient was tested by Wechsler Adult Intelligence Scale Revised in China (WAIS-RC) in 40 severe head injury patients. Auditory P300 was measured in 40 normal healthy people as control group.
Results:
The latencies of P300 in severe head injury patients group were longer than in control group. There was a significant difference between the two groups (P< 0.01). There were significant negative correlations between P300 latency and VIQ and FIQ respectively (r=-0.335,-0.344, P<0.05).
Conclusion:
ERP might be taken as an objective index for measuring the change of the brain cognition function in patients with severe head injury.
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