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Updated: Jul 13, 2026
07:01
Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Synostosis between pubic bones due to neurogenic, heterotopic ossification
Subramanian Vaidyanathan1, Peter L Hughes, Bakul M Soni
1Regional Spinal Injuries Centre, District General Hospital, Southport, UK. S.Vaidyanathan@southportandormskirk.nhs.uk
Thescientificworldjournal
|July 11, 2007
Summary
Neurogenic heterotopic ossification, a rare bone formation in soft tissue, occurred in a patient with spina bifida. This ectopic bone formation complicated suprapubic cystostomy by causing Foley catheter balloon rupture.
Area of Science:
- Urology
- Orthopedics
- Neurology
Background:
- Neurogenic heterotopic ossification involves ectopic bone formation in patients with neurological disorders.
- A 33-year-old female with spina bifida and paraplegia presented with urinary issues.
- She underwent suprapubic cystostomy due to chronic urine leakage.
Observation:
- The patient experienced persistent urine leakage around the suprapubic catheter despite interventions.
- X-rays and CT scans revealed heterotopic bone formation bridging pubic diastasis.
- The ectopic bone's sharp edge was implicated in frequent Foley catheter balloon ruptures.
Findings:
- Heterotopic ossification in the pubic region was temporally linked to suprapubic cystostomy and urine leak.
- Complications included frequent Foley balloon rupture and difficulty with suprapubic catheter insertion.
- The ossification led to synostosis between the pubic bones.
Implications:
- This case suggests urinary tract-related factors may contribute to heterotopic ossification.
- Understanding these unique risk factors is crucial for managing neurological patients with urinary diversions.
- Further research is needed to explore the link between chronic urine leaks and ectopic bone formation.
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