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Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II

Carmel B Stober1, Sven Brode, Jacqueline K White

  • 1Cambridge Institute for Medical Research and Department of Medicine, Wellcome Trust/MRC Building, University of Cambridge School of Clinical Medicine, Addenbrookes Hospital, Hills Road, Cambridge CB2 2XY, United Kingdom.

Infection and Immunity
|July 11, 2007
PubMed
Summary

Solute carrier family 11 member a1 (Slc11a1) in dendritic cells influences immune responses. Wild-type Slc11a1 enhances antigen presentation and may protect against infections but increase type 1 diabetes risk.

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