Study on the interrelationship between 5-HTTLPR/G-protein beta3 subunit (C825T) polymorphisms and depressive disorder

Mei-Qun Cao1, Sui-Yu Hu, Chun-Hu Zhang

  • 1Research Institute of Integrated Traditional Chinese and Western Medicine, Xiang Ya Hospital, Central South University, Changsha, Hunan, Republic of China. caomeiqun@yahoo.com.cn

Psychiatric Genetics
|July 11, 2007
PubMed
Summary

Genetic variations in the serotonin transporter gene (5-HTTLPR) and G-protein beta3-subunit (GNbeta3 C825T) are linked to a higher risk of depressive disorder. An interaction between these gene variants may further increase susceptibility.

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