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Overview of immunological studies on A-bomb survivors
M Akiyama1, Y Kusunoki, S Kyoizumi
1Radiation Effects Research Foundation, Hiroshima, Japan.
Journal of Radiation Research
|March 1, 1991
Abstract:
Among the peripheral blood lymphocytes, T-cells and B-cells significantly decreased in number with age. Radiation exposure resulted in further significant decrease of T-cell count (but not B cells) in the elderly. T-cell response to PHA and allo-antigens also decreased with dose in the elderly group. In contrast, NK cell number and function increased with age while a significant dose effect was not observed.