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Updated: Jul 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Intra-arterial thrombolysis in a 2-year-old with cardioembolic stroke
Susan L Benedict1, Oliver K Ni, Peter Schloesser
1Department of Pediatrics, University of Utah, Primary Children's Medical Center, Salt Lake City, Utah 84158, USA. susan.benedict@hsc.utah.edu
Abstract:
Recombinant tissue plasminogen activator, although the standard of care for the management of acute ischemic stroke in adults, is used infrequently in children. The authors describe the use of intra-arterial recombinant tissue plasminogen activator in a young child with embolic stroke. Thrombolysis restored flow to the affected middle cerebral artery and appeared to limit the extent of the infarction and the severity of the subsequent neurologic deficits.
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