Related Experiment Video
Updated: Jul 13, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Management of overactive bladder syndrome
Sushma Srikrishna1, Dudley Robinson, Linda Cardozo
1Department of Urogynaecology, King's College Hospital, Denmark Hill, London, UK. sushmasrikrishna@hotmail.com
Overactive bladder (OAB) syndrome, characterized by urinary urgency, is commonly treated with medications. This review focuses on newer medical treatments for OAB in women, exploring options beyond conservative and surgical interventions.
Area of Science:
- Urology
- Gynecology
Background:
- Overactive bladder (OAB) syndrome presents as urinary urgency, often with frequency and nocturia.
- Current management includes conservative measures, pharmacotherapy, and surgery as a last resort.
Purpose of the Study:
- To review the management of overactive bladder (OAB) in women.
- To specifically focus on recent advancements in the medical treatment of OAB.
Main Methods:
- Literature review of OAB management strategies.
- Emphasis on pharmacological interventions for OAB in women.
Main Results:
- Drug treatment remains a key component in managing OAB in women.
- Newer developments in medical therapies are expanding treatment options.
Conclusions:
- Medical management is crucial for OAB, with ongoing research into novel treatments.
- A comprehensive approach, including conservative and surgical options, is essential for intractable cases.
Related Concept Videos
Urinary Tract Infection IV: Nursing Management
Irritable Bowel Syndrome III: Medical and Nursing Management
Urinary Tract Calculi III: Medical Management
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...
Urinary Tract Calculi V: Nursing Management
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...