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Updated: Jul 13, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Sudden temperature changes and respiratory symptoms--an experimental approach
Gustavo Silveira Graudenz1, Celso Henrique Oliveira, Arlindo Tribess
1Division of Allergy and Clinical Immunology, Internal Medicine Department, School of Medicine, Millennium Institute, University of Sao Paulo, Sao Paulo- SP, Brazil. gustavog@usp.br
Individuals with allergic rhinitis experience more respiratory and eye symptoms from sudden temperature changes common in air-conditioning. This suggests a lower tolerance threshold for those with allergic rhinitis.
Area of Science:
- Environmental Health
- Allergology
- Respiratory Medicine
Background:
- Indoor air quality (IAQ) and allergic conditions are known risk factors for respiratory issues.
- Air-conditioning systems can induce sudden temperature fluctuations, impacting respiratory health.
Purpose of the Study:
- To investigate the influence of allergic rhinitis on respiratory complaints.
- To compare symptom development in allergic rhinitis patients versus controls under varying temperatures.
Main Methods:
- A case-control study involving 32 allergic rhinitis patients and 16 controls.
- Subjects were exposed to alternating hot (26°C) and cold (14°C) temperatures in controlled chambers.
- Symptoms and peak flow rates (nasal, pulmonary) were measured before, during, and after exposure.
Main Results:
- Allergic rhinitis patients reported increased eye itching/stinging and breathlessness, particularly in hot conditions.
- Significant reductions in expiratory flow rates were observed in the rhinitis group during both hot and cold exposures.
- These flow rate reductions persisted for 24 hours post-exposure.
Conclusions:
- Individuals with allergic rhinitis exhibit a heightened sensitivity to temperature shifts.
- Air-conditioning-induced temperature changes can trigger respiratory and ocular symptoms in allergic rhinitis patients at a lower threshold.
- Findings highlight the importance of temperature control for managing allergic rhinitis symptoms indoors.
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