Self-reported medical conditions in perfluorooctanesulfonyl fluoride manufacturing workers
Mira M Grice1, Bruce H Alexander, Richard Hoffbeck
1University of Minnesota, School of Public Health, Division of Environmental Health Sciences, Minneapolis, Minnesota 55455, USA.
Objective:
To evaluate whether some cancers, other conditions, and pregnancy outcomes were related to occupational perfluorooctane sulfonate (PFOS) exposure.
Methods:
We surveyed current and former employees of a perfluorooctanesulfonyl fluoride production facility, using a self-administered questionnaire to ascertain several cancers and health conditions. Female cohort members also completed a brief pregnancy history. We requested medical records to validate reported melanoma, breast, prostate, and colon cancers. PFOS exposure was estimated based on a job exposure matrix up to the year of the diagnosis of the condition.
Results:
Of the 1,895 eligible participants, 1,400 questionnaires were returned. No association was observed between working in a PFOS-exposed job and the risk of any of the surveyed conditions.
Conclusion:
We observed no association between working in a PFOS-exposed job and several cancers, common health conditions, and birth weight.
More Related Videos
07:06Investigating Long-Distance Transport of Perfluoroalkyl Acids in Wheat via a Split-Root Exposure Technique
Published on: September 28, 2022
09:29An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
Published on: May 13, 2020
