Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Stationary phase characterization and method development.

¹Waters Corporation, Milford, MA 01757, USA. Uwe_Neue@Waters.com

Journal of Separation Science

|July 12, 2007

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comment on "Submicrometer plate heights for capillaries packed with silica colloidal crystals".

Analytical chemistry·2010

Same author

The determination of the plate count for large molecules under reversed-phase gradient conditions.

Journal of chromatography. A·2010

Same author

Ultra-performance liquid chromatography technology and applications.

Advances in chromatography·2010

Same author

Influence of pressure on the retention of sugars in hydrophilic interaction chromatography.

Journal of separation science·2009

Same author

Further investigations of the effect of pressure on retention in ultra-high-pressure liquid chromatography.

Journal of chromatography. A·2009

Same author

Effects of extra-column band spreading, liquid chromatography system operating pressure, and column temperature on the performance of sub-2-microm porous particles.

Journal of chromatography. A·2009

Same journal

A High-Throughput Analytical Approach Using Polyaniline Doped With Oxalic Acid in Thin Film Solid-Phase Microextraction for the Determination of Personal Care Products in Recreational Waters.

Journal of separation science·2026

Same journal

Simultaneous Determination of Dechlorane-Related Compounds in Fish Muscle by Microwave-Assisted Extraction Combined With Enhanced Matrix Removal for Lipids Cleanup and Gas Chromatography-Tandem Mass Spectrometry.

Journal of separation science·2026

Same journal

Covalent Zwitterionic Peptide-Based Antifouling Coating of the Fused Silica Capillary Applied for CE Separation of Proteins.

Journal of separation science·2026

Same journal

Pharmacokinetic Study of Five Lead Components of Psoraleae Fructus in Human Serum by UHPLC-Q-TOF-MS and UHPLC-QqQ-MS/MS after Oral Administration of Qing'e Pills.

Journal of separation science·2026

Same journal

Passive Blood-Plasma Separation via Constriction-Expansion Geometry in Untreated Paper Microfluidic Devices.

Journal of separation science·2026

Same journal

Construction of Nitrogen-rich Graphene Oxide/Chitosan Adsorbent for the Removal of Hexavalent Chromium from Wastewater.

Journal of separation science·2026

See all related articles

Recent advancements offer new stationary phase characterization methods for chromatography. This review highlights parallel parameter approaches and the strategic use of temperature in method development for improved analytical outcomes.

Area of Science:

Analytical Chemistry
Chromatography

Background:

Stationary phases are critical in chromatography, influencing separation efficiency.
Characterization methods ensure consistent performance and aid in method development.

Purpose of the Study:

To review recent developments in stationary phase characterization methods.
To discuss new approaches in chromatographic method development, including parallel parameter analysis and temperature optimization.

Main Methods:

Review of literature on stationary phase properties and characterization techniques.
Analysis of new characterization methodologies and their comparative differences.
Survey of modern method development strategies, focusing on multi-parameter and temperature-based approaches.

Related Experiment Videos

Main Results:

Emergence of novel and significant characterization methods for stationary phases.
Identification of key differences and advantages among various characterization techniques.
Increased utilization of parallel parameter screening and temperature manipulation in method development.

Conclusions:

The field of stationary phase characterization has seen substantial innovation.
Advanced characterization and method development strategies enhance chromatographic analysis.
Temperature is re-emerging as a valuable and versatile tool in optimizing chromatographic separations.