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Published on: October 29, 2014
Campylobacter fetus subspecies fetus infection
F Allerberger1, M J Kasten, J P Anhalt
1Section of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota.
Abstract:
During a six-year period five patients with Campylobacter fetus subspecies fetus infections were seen at the Mayo Clinic in Rochester, Minnesota. Bacteremia was observed in two patients, one presenting with aortic valve endocarditis and the other with abdominal atherosclerotic aortic aneurysm. C. fetus subsp. fetus was isolated from tibial tissue of a patient with osteomyelitis. Diarrhea was the main complaint of two further patients, and was also mentioned by the patient with the aortic aneurysm. Despite the use of incubation conditions and selective media geared to detect only Campylobacter jejuni, C. fetus subsp. fetus was isolated from stool specimens of the two patients with gastrointestinal symptoms. The fact that three of five C. fetus subsp. fetus infections observed in this study were associated with intestinal symptoms further supports the importance of the gastrointestinal tract in the pathogenesis of C. fetus subsp. fetus infections.
Insights
Campylobacter fetus subspecies fetus infections can cause serious conditions like bacteremia and osteomyelitis. The gastrointestinal tract appears to be a significant source for these infections, even when testing targets other bacteria.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Campylobacter fetus subspecies fetus is an opportunistic pathogen.
- Infections are often associated with specific risk factors or underlying conditions.
Purpose of the Study:
- To report on cases of Campylobacter fetus subspecies fetus infections observed over a six-year period.
- To investigate the clinical presentations and sources of these infections.
Main Methods:
- Retrospective case review of patients diagnosed with Campylobacter fetus subspecies fetus infections.
- Analysis of clinical data, including symptoms, diagnoses, and microbiological findings.
- Evaluation of isolation techniques for Campylobacter species from various sample types.
Main Results:
- Five cases of Campylobacter fetus subspecies fetus infection were identified.
- Infections included bacteremia (aortic valve endocarditis, abdominal aortic aneurysm), osteomyelitis, and gastrointestinal symptoms (diarrhea).
- The pathogen was successfully isolated from stool specimens despite standard methods targeting Campylobacter jejuni.
Conclusions:
- Campylobacter fetus subspecies fetus can cause severe systemic infections.
- The gastrointestinal tract is an important reservoir and potential source for Campylobacter fetus subspecies fetus infections.
- Clinical microbiology laboratories should consider C. fetus subsp. fetus in the differential diagnosis of relevant infections.
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