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Published on: May 6, 2018
[Antiviral drug-induced nephrotoxicity]
Ricardo Neto1, Gerardo Oliveira, Manuel Pestana
1Serviço de Nefrologia, Hospital de São João, Porto, Portugal.
Acta Medica Portuguesa
|July 13, 2007
Summary
Antiviral medications can harm the kidneys, leading to acute kidney injury. This review covers how these drugs cause kidney damage, their symptoms, and how to prevent and treat this condition.
Area of Science:
- Nephrology
- Pharmacology
- Toxicology
Context:
- Increasing incidence of acute kidney injury (AKI) associated with antiviral drug use.
- Growing concern regarding nephrotoxicity from antiviral therapies.
- Need for comprehensive understanding of drug-induced kidney damage.
Purpose:
- To review the pathogenesis of antiviral drug-induced kidney injury.
- To describe the clinical manifestations of antiviral drug-induced nephrotoxicity.
- To outline prevention and treatment strategies for antiviral drug-induced kidney damage.
Summary:
- Antiviral drug-induced kidney injury is a significant clinical issue, often resulting in acute renal failure.
- The review details the mechanisms by which antiviral drugs damage the kidneys.
- Clinical signs and symptoms of this nephrotoxicity are discussed, alongside management approaches.
Impact:
- Provides a consolidated resource for clinicians managing patients on antiviral therapy.
- Aims to improve patient outcomes by highlighting preventative measures and treatment options.
- Contributes to the understanding of drug-induced kidney disease, informing future research and clinical practice.
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