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Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
Published on: September 23, 2022
Chimeric T helper-B cell peptides induce protective response against Japanese encephalitis virus in mice
Shailesh Shyam Dewasthaly1, Gauri Sanjay Bhonde, Vasudha Shankarraman
1National Institute of Virology, Pune 411 001, India.
Protein and Peptide Letters
|July 14, 2007
Abstract:
Virus neutralizing MAb binding and T helper cell stimulating peptide epitopes from structural and non-structural proteins of Japanese encephalitis virus were delineated. It was observed that priming by T helper peptides potentiated neutralizing antibody response against JE virus. Immunization with chimeric T helper - B cell peptides could thus protect mice from lethal challenge with JE virus.

