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Repolarization gradients and arrhythmogenicity in the murine heart

Matthew J Killeen1, Ian N Sabir

  • 1Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK. mjk42@cam.ac.uk

The Journal of Physiology
|July 14, 2007
PubMed
Abstract

No abstract available in PubMed .

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.