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[Pulmonary abscess and Pyoderma gangrenosum].

A Mirkamali1, B Martha, Y Dutronc

  • 1Service des maladies infectieuses et tropicales, CHU de Dijon, 10, boulevard Maréchal-de-Lattre-de-Tassigny, 21079 Dijon cedex, France.

Medecine Et Maladies Infectieuses
|July 14, 2007
PubMed
Summary
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Pyoderma gangrenosum, a neutrophilic dermatosis, can manifest initially as non-infectious lung abscesses. Cutaneous lesions may appear months later, highlighting the importance of considering extracutaneous origins for lung abscesses.

Area of Science:

  • Dermatology
  • Pulmonology
  • Immunology

Background:

  • Pyoderma gangrenosum (PG) is an ulcerative condition within neutrophilic dermatoses.
  • Common extracutaneous sites include the lungs, joints, and digestive tract.

Observation:

  • A case of PG initially presented as an aseptic lung abscess.
  • Cutaneous lesions appeared nine months after the lung manifestation, located on the thorax and surgical scars.
  • Diagnosis was confirmed via skin biopsies; IgA monoclonal gammopathy was the only associated finding.

Findings:

  • The case demonstrates that lung abscesses can have non-infectious etiologies.
  • Extracutaneous manifestations of PG, such as lung abscesses, can precede skin lesions by several months.

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Implications:

  • This report emphasizes considering non-infectious causes for lung abscesses.
  • It highlights the potential for delayed cutaneous presentation in Pyoderma gangrenosum, with pulmonary involvement being a frequent extracutaneous manifestation.