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Published on: June 2, 2023
Plasma cytokine levels in ulcerative colitis
Vedat Goral1, Tahir Celenk, Abdurahman Kaplan
1Department of Gastroenterology, Dicle University School of Medicine, Diyarbakir, Turkey. vegoral@hotmail.com
Background/Aims:
Some immunological factors are responsible in the pathogenesis of ulcerative colitis. There is a relationship between cytokines and ulcerative colitis.
Methodology:
In this study 20 ulcerative colitis patients (mean age 36.2 years old, 9 women, 11 men) and 20 healthy control groups (mean age 27.2 years old, 11 women, 9 men) were involved in the study.
Results:
We established that IL-2Rsp, IL-6, IL-8 and IL-10 levels were different at the patients and control groups (p < 0.005). TNF-alpha and IL-1 beta were similar at the both groups.
Conclusions:
According to these results, IL-2Rsp, IL-6, 11-8 and IL-10 play an important role in the pathogenesis of ulcerative colitis. We consider that these cytokines are beneficial parameters in the diagnosis, treatment and prognosis of ulcerative colitis.
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