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Updated: Jul 13, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[A case report on canceration of proliferative verrucous leukoplakia]
Lin Ge1, Hong-Mei Zhou, Xin Zeng
1Dept. of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
Abstract:
Proliferative verrucous leukoplakia (PVL) is a particular form of oral leukoplakia clinically characterized by chronic proliferation, multiple occurrence, and intractability. It is seen mostly among elderly women and often involves bucca, palate, gingiva and tongue. Its canceration rate is very high. This article reports a case of a middle-aged woman with progressive PVL which became focally malignant who complained about buccal and palatal exophytic white patches, and discusses the possible pathogenic mechanism, diagnosis, treatment, prognosis of PVL and differentiation between PVL and other types of oral leukoplakia by way of reviewing relevant literature.
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