Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[POEMS syndrome].

Martin Soubrier1

  • 1Service de rhumatologie, Hôpital Gabriel Montpied, CHU, Clermont-Ferrand. msoubrier@chu-clermontferrand.fr

Presse Medicale (Paris, France : 1983)
|July 17, 2007
PubMed
Summary
This summary is machine-generated.

POEMS syndrome is a rare disorder characterized by polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. Elevated vascular endothelial growth factor (VEGF) is a key feature, influencing treatment strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal incidence of native septic arthritis in France: a 13-year analysis of the National Health Data System Database.

Rheumatology (Oxford, England)·2026
Same author

Ocrelizumab in a difficult-to-treat rheumatoid arthritis patient.

Clinical and experimental rheumatology·2026
Same author

Smartphone-related pain and discomfort in hand osteoarthritis, rheumatoid arthritis, and psoriatic arthritis: results from the monocentric cross-sectional PHONERIC study.

Rheumatology international·2025
Same author

Baseline characteristics of the TRANSLATE2 cohort: A prospective study on rheumatoid arthritis-associated interstitial lung disease.

Joint bone spine·2025
Same author

Effects of face-to-face and remote Tai Chi in stable axial spondyloarthritis: a pilot randomised controlled trial.

Rheumatology international·2025
Same author

Effect of a 1-month methotrexate delay on pneumococcal vaccine immunogenicity and disease control in patients with early rheumatoid arthritis (VACIMRA): an open-label randomised trial.

The Lancet. Rheumatology·2025
Same journal

Predictive analytics and risk stratification models in internal medicine: from risk scores to real-time machine learning.

Presse medicale (Paris, France : 1983)·2026
Same journal

Artificial Intelligence in skin disease therapeutics: from drug discovery to personalized treatment pathways.

Presse medicale (Paris, France : 1983)·2026
Same journal

AI in clinical diagnostics in dermatology: applications, validation, and real-world use cases.

Presse medicale (Paris, France : 1983)·2026
Same journal

Artificial Intelligence in medical research and publishing: progress, risks, and future perspectives.

Presse medicale (Paris, France : 1983)·2026
Same journal

Ethical, legal, and regulatory challenges in AI-based healthcare tools.

Presse medicale (Paris, France : 1983)·2026
Same journal

Decision-making for clinicians.

Presse medicale (Paris, France : 1983)·2026
See all related articles

Area of Science:

  • Hematology
  • Neurology
  • Endocrinology

Context:

  • POEMS syndrome is a rare multisystem disorder.
  • It presents with a distinct constellation of symptoms including polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes.
  • Other potential manifestations include fluid overload, fever, and organ damage.

Purpose:

  • To summarize the key features, pathogenesis, and treatment of POEMS syndrome.
  • To highlight the role of vascular endothelial growth factor (VEGF) in POEMS syndrome.
  • To discuss current and potential therapeutic approaches.

Summary:

  • POEMS syndrome combines polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy (or plasma cell disorder), and skin changes.
  • Elevated vascular endothelial growth factor (VEGF) is a hallmark of the syndrome.

Related Experiment Videos

  • Treatment is tailored to the individual, including radiation, transplantation, chemotherapy, and potentially novel agents like thalidomide and bevacizumab.

    • Impact:

    • Provides a comprehensive overview of POEMS syndrome for clinicians and researchers.
    • Emphasizes the importance of VEGF in understanding the disease.
    • Informs treatment decisions for refractory cases and guides future research directions.