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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

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Steroid-induced glaucoma in an infant.

Kelly A Hutcheson¹

¹Children's National Medical Center and George Washington University School of Medicine, Washington, DC 20010, USA. khutches@cnmc.org

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus

|July 17, 2007

Summary

Topical steroid eye drops can cause increased intraocular pressure and glaucoma in infants. This condition resolved after stopping the steroid medication, highlighting infant sensitivity.

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Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

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Area of Science:

Ophthalmology
Pediatric Medicine
Pharmacology

Background:

Topical corticosteroids are widely used for ocular inflammation.
Infants and young children may have unique sensitivities to medications.
Intraocular pressure (IOP) monitoring is crucial during corticosteroid therapy.

Observation:

A 3-week-old infant presented with buphthalmos (enlarged eye) and glaucoma.
The infant had received a 1-week course of topical steroid eye drops.
Buphthalmos and glaucoma are signs of pediatric glaucoma.

Findings:

The infant's glaucoma was directly linked to the topical steroid use.
Intraocular pressure normalized after discontinuation of the steroid medication.
This indicates a rapid and reversible steroid-induced ocular hypertension.

Implications:

Infants and very young children are highly susceptible to steroid-induced IOP elevation.
Careful monitoring for glaucoma is essential in infants treated with topical steroids.
Alternative anti-inflammatory treatments may be considered for pediatric ocular conditions.