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Updated: Jul 13, 2026
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Incidental MRI detection of BRCA1-related solitary peritoneal carcinoma during breast screening--A case report
Kimberley A Hill1, Barry Rosen, Patricia Shaw
1Division of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, T2 053, Toronto, Ontario, Canada M4N 3M5. kimberley.hill@sunnybrook.ca
Background:
The reported cumulative risk of developing primary peritoneal carcinoma (PPC) one to 20 years after prophylactic bilateral oophorectomy is 3.5% to 4.3%. Virtually all reported cases have been stage III or IV.
Case:
During MRI screening of the breasts, an incidental mass on the surface of the liver was identified in a 56-year-old BRCA1 mutation carrier who had undergone prophylactic bilateral salpingo-oophorectomy several years previously with no evidence of malignancy. After four cycles of chemotherapy a localized, grade 3 serous papillary adenocarcinoma was resected followed by further chemotherapy and radiation. She remains disease-free 3 years post-treatment.
Conclusion:
The literature on PPC after prophylactic oophorectomy is reviewed. To the best of our knowledge, this is the first description of an apparently localized case of BRCA related PPC outside the pelvis.
