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[Open leg fracture with Bacillus cereus infection]
L Nguyen1, V Minville, H Bensafi
1Département d'anesthésie et de réanimation, CHU de Toulouse, hôpital Rangueil, université Paul-Sabatier, Toulouse, France.
Annales Francaises D'Anesthesie Et De Reanimation
|July 17, 2007
Summary
Bacillus cereus is an emerging pathogen in leg fracture infections, particularly those with environmental contamination. Standard prophylactic antibiotics are ineffective, necessitating screening and ciprofloxacin treatment for open fractures.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Context:
- Leg fractures present a significant risk for bacterial infections in orthopedic settings.
- Bacillus cereus (B. cereus) has been identified as a causative agent in some fracture-related infections.
- University hospital traumatology-orthopedic wards manage a high volume of fracture cases.
Purpose:
- To investigate the prevalence and characteristics of leg fractures infected with Bacillus cereus.
- To evaluate the effectiveness of prophylactic chemotherapy against B. cereus in fracture patients.
- To inform clinical practice regarding the management of B. cereus infections in trauma cases.
Summary:
- A retrospective study analyzed 34 patients with leg fractures infected by B. cereus between 1995 and 2004.
- Isolates were primarily from patients with fractures contaminated by terrestrial environments (telluric contamination).
- Betalactam antibiotics showed ineffectiveness against B. cereus, highlighting treatment challenges.
Impact:
- Bacillus cereus is recognized as an emerging pathogen in orthopedic trauma.
- Systematic screening for B. cereus in open fractures with telluric contamination is recommended.
- Ciprofloxacin is suggested as the preferred chemotherapy for B. cereus infections, administered for 2-6 weeks.
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