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Related Experiment Videos

Pseudoxanthoma elasticum.

Harith Akram1, Mathew D Sewell2, Leo H H Cheng3

  • 1Oral & Maxillofacial Surgery, Bart's and The London NHS Trust/The Homerton University Hospital, United Kingdom.

The British Journal of Oral & Maxillofacial Surgery
|July 17, 2007
PubMed
Summary
This summary is machine-generated.

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Pseudoxanthoma elasticum (PXE) can cause significant skin laxity. This case highlights surgical management for severe neck skin changes in a PXE patient.

Area of Science:

  • Dermatology
  • Plastic Surgery
  • Genetics

Background:

  • Pseudoxanthoma elasticum (PXE) is a rare genetic disorder affecting elastic tissues.
  • PXE can manifest with characteristic skin changes, including excessive wrinkling and laxity.
  • Neck involvement in PXE, while not uncommon, presents unique challenges for surgical correction.

Observation:

  • A 44-year-old Afro-Caribbean woman with PXE presented with severe, premature wrinkling and loosening of the neck skin.
  • The patient's symptoms significantly impacted her quality of life and appearance.
  • Clinical examination revealed characteristic "cobblestone" appearance in affected areas.

Findings:

  • Surgical intervention involving platysmoplasty and bilateral neck lift was performed.

Related Experiment Videos

  • A subsequent latent excision of nuchal skin folds addressed residual laxity.
  • The procedures aimed to restore a more youthful and aesthetically pleasing contour to the neck.

    • Implications:

    • This case demonstrates the feasibility and potential effectiveness of surgical correction for severe neck deformities in PXE patients.
    • It underscores the importance of a multidisciplinary approach involving dermatologists and plastic surgeons.
    • Further research into long-term outcomes and optimal surgical techniques for PXE-related skin manifestations is warranted.