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Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing
Published on: October 15, 2014
Selective use of blood cultures in emergency department pneumonia patients
Ronald S Benenson1, Andrew M Kepner, Donald N Pyle
1Department of Emergency Medicine, York Hospital, York, Pennsylvania 17405, USA.
Abstract:
Our objectives were to identify factors associated with positive blood cultures and to evaluate blood culture use in the management of hospitalized pneumonia patients to limit their use. A retrospective chart review was conducted at a community teaching hospital. Emergency Department patients with an admission diagnosis of pneumonia during calendar years 2001-2002 were included. Patients younger than age 18 years and those with a non-pneumonia discharge diagnosis were excluded. Of 684 eligible patients, 23 (3.4%) had true positive blood cultures. All organisms were sensitive to empiric antibiotics. Three risk factors were associated with positive blood cultures: oxygen saturation < 90%, serum sodium < 130 and respiratory rate > 30 breaths/min. No patient had antibiotic coverage broadened based on blood culture results. Positive blood culture rates were low and did not affect the clinical management of pneumonia patients. We recommend eliminating blood cultures in community-acquired pneumonia (CAP) patients, but obtaining blood cultures in patients at risk for multi-drug resistant pathogens, such as health-care-associated pneumonia (HCAP) patients.
Insights
Blood cultures rarely yielded positive results in hospitalized pneumonia patients and did not alter treatment. Researchers suggest limiting blood cultures for community-acquired pneumonia (CAP) but continuing them for healthcare-associated pneumonia (HCAP) cases.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Hospital Epidemiology
Background:
- Blood cultures are frequently used in managing hospitalized pneumonia patients.
- The utility and impact of routine blood cultures in pneumonia management require evaluation.
Purpose of the Study:
- To identify factors associated with positive blood cultures in pneumonia patients.
- To assess the impact of blood culture results on antibiotic management.
- To evaluate the necessity of blood cultures in hospitalized pneumonia cases.
Main Methods:
- Retrospective chart review of Emergency Department patients with pneumonia.
- Inclusion criteria: adults admitted with pneumonia, 2001-2002.
- Exclusion criteria: age < 18, non-pneumonia discharge diagnosis.
Main Results:
- A low rate of true positive blood cultures (3.4%) was observed.
- Identified risk factors for positive blood cultures: low oxygen saturation (<90%), low serum sodium (<130), and high respiratory rate (>30).
- Blood culture results did not lead to changes in empiric antibiotic coverage.
Conclusions:
- Routine blood cultures in community-acquired pneumonia (CAP) may not be necessary due to low yield and lack of impact on management.
- Blood cultures remain important for patients at risk for multi-drug resistant pathogens, such as healthcare-associated pneumonia (HCAP) patients.
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