Related Experiment Videos
Propionibacterium acnes and SAPHO syndrome: a case report and literature review
M Colina1, A Lo Monaco, M Khodeir
1Sezione di Reumatologia, Dipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Ferrara, and Dipartimento di Patologia ed Oncologia, Azienda Ospedaliera/Universitaria Arcispedale Sant'Anna, Ferrara, Italy. teocolina@libero.it
Objective:
To describe the presence of Propionibacterium acnes (P. acnes) in a series of patients with SAPHO syndrome in which a bone biopsy has been carried out and to discuss the results comparing them to the data described in the literature.
Methods:
In 6 out of 56 patients with SAPHO syndrome, a bone biopsy from osteitic lesion was carried out. This invasive investigation was performed only in those cases in which it was necessary to clarify the diagnosis.
Results:
Of the 6 biopsies processed, P. acnes was isolated in only one case. No other infectious agents were identified.
Conclusion:
P. acnes is not often found in bone lesions of SAPHO syndrome. A bone biopsy may represent a procedure useful for corroborating the diagnosis or for excluding other diseases only in specific cases.
Related Concept Videos
Staphylococcal Skin Infections
Acne Infection
The Skin Microbiota
Accessory Structures of the Skin: Sebaceous Glands
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Clinical Significance of Antibiotic Resistance
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...