Related Experiment Video
Updated: Jul 13, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
[Epidemiology and clinical characteristics of childhood parapneumonic empyemas]
A Desrumaux1, P François, C Pascal
1Département de pédiatrie, CHU de Grenoble, 38043 Grenoble, France.
Insights
The incidence of complicated childhood pneumonia, including parapneumonic empyema, significantly increased in a French region from 1995 to 2003. Further research is needed to determine the causes of this rise in pediatric cases.
Area of Science:
- Pediatric infectious diseases
- Respiratory medicine
- Epidemiology
Context:
- Childhood parapneumonic empyema incidence is rising globally.
- Community-acquired pneumonia (CAP) can lead to severe complications in children.
- Understanding regional trends in pediatric CAP complications is crucial for public health.
Purpose:
- To estimate the annual incidence of complicated CAP in children in a French region over nine years (1995-2003).
- To describe the epidemiological and clinical features of these pediatric pneumonia complications.
- To identify trends in childhood empyema and lung abscess hospitalizations.
Summary:
- A 9-year study (1995-2003) in the Isere district, France, analyzed 90 hospitalizations for complicated CAP in children (28 days to 15 years).
- Complications included 83 pleural empyemas and 7 lung abscesses.
- The incidence of complicated pneumonia rose from 0.5 to 13 per 100,000 children, with a significant increase noted since 1999 (P<0.001).
Impact:
- This study highlights a significant increase in complicated pediatric pneumonia in France, necessitating further investigation into causative factors.
- Findings underscore the importance of monitoring pediatric respiratory infections and their complications.
- The data provides valuable epidemiological insights for pediatric pulmonologists and public health officials.
Unlabelled:
Several studies have reported an increasing incidence of childhood parapneumonic empyemas in various countries.
Aim Of The Study:
The aim of our study was to estimate the annual incidence of complicated community-acquired pneumonias in children during a 9-year period in a French area and to describe the epidemiological and clinical characteristics of these complications.
Population And Methods:
We have listed the children from 28 days to 15 years old, hospitalized in the 2 children hospitals of the Isere district for a community-acquired pneumonia complicated with a pleural empyema or a pulmonary abscess from 1995 to 2003.
Results:
During the study period, 90 children were hospitalized for a complicated pneumonia including 83 pleural empyemas and 7 isolated lung abscess. The average number of cases was 4 per year from 1995 to 1998 then increased since 1999 to reach 34 cases in 2003, according to a linear model (P<0,001). The incidence of the complicated pneumonia, plotted to the paediatric population of the area has gone up from 0.5 per 100000 to 13 per 100000 children between 1995 and 2003.
Conclusion:
The incidence of the complicated pneumonias in children increased since 1999 in a French area. Additional investigations are necessary to identify the causes of this increase.
Related Concept Videos
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Atypical Pneumonia
Pneumonia II: Pathophysiology
Pneumonia III: Complications and Assessment
Chronic Obstructive Pulmonary Disease II: Emphysema