Related Experiment Video

Updated: Jul 13, 2026

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
10:24

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins

Published on: September 28, 2012

Bid plays a role in the DNA damage response

Sandra S Zinkel, Kristen E Hurov, Atan Gross

    Cell
    |July 17, 2007
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage10:44

    Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

    Published on: January 31, 2018

    Visualization of DNA Repair Proteins Interaction by Immunofluorescence07:55

    Visualization of DNA Repair Proteins Interaction by Immunofluorescence

    Published on: June 26, 2020

    Related Concept Videos

    DNA Damage Can Stall the Cell Cycle02:36

    DNA Damage Can Stall the Cell Cycle

    In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
    DNA Damage can Stall the Cell Cycle02:36

    DNA Damage can Stall the Cell Cycle

    In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
    Nucleotide Excision Repair01:38

    Nucleotide Excision Repair

    DNA Distortion and Damage
    Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
    Nucleotide Excision Repair01:08

    Nucleotide Excision Repair

    Overview
    Nucleotide Excision Repair01:08

    Nucleotide Excision Repair

    Overview
    Base Excision Repair01:54

    Base Excision Repair

    One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
    The first step of...