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[Age-related changes in cardiac performance index (TEI index) with special reference to the difference between the

Teru Nada1, Nobuo Fukuda, Yasuo Yamaguchi

  • 1Department of Cardiology and Clinical Research, National Hospital Organization Zentsuji Hospital, Senyu-cho 2-1-1, Zentsuji, Kagawa 765-8507.

Journal of Cardiology
|July 19, 2007
PubMed

Insights

The Tei index, a measure of cardiac performance, increases with age, particularly in the left ventricle, due to prolonged relaxation time. This age-related change is crucial for accurate clinical interpretation.

Area of Science:

  • Cardiology
  • Gerontology
  • Echocardiography

Background:

  • The Tei index assesses combined systolic and diastolic cardiac function.
  • Age-related changes in the Tei index are not well-established.
  • Understanding these changes is vital for clinical applications.

Purpose of the Study:

  • To investigate age-related changes in the Tei index.
  • To compare age-related differences between the left and right ventricles.

Main Methods:

  • Ninety-nine healthy subjects (14-89 years) underwent pulsed Doppler echocardiography.
  • Isovolumic contraction time (ICT), isovolumic relaxation time (IRT), and ejection time (ET) were measured for both ventricles.
  • The Tei index was calculated as (ICT + IRT) / ET.

Main Results:

  • IRT and Tei index showed a direct correlation with age in both ventricles, stronger in the left ventricle.
  • No age correlation was found for ICT and ET.
  • Abnormal Tei index values (>0.47) increased with age in the left ventricle (10% in 6th-7th decades, 24% in 8th-9th decades), but remained normal in the right ventricle.

Conclusions:

  • The Tei index increases with age, primarily in the left ventricle, linked to prolonged IRT and relaxation abnormalities.
  • Clinical interpretation of the Tei index must account for age-related effects.
Abstract

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