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Related Experiment Video

Updated: Jul 13, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

[Bleeding oesophageal varices--therapeutic options].

A R Pavlović¹, M Krstić, S Djuranović

¹Institut za bolesti digestivnog sistema, Klinika za gastroenterologiju i hepatologiju, KCS, Beograd.

Acta Chirurgica Iugoslavica

|July 20, 2007

Summary

Emergency endoscopy is crucial for esophageal variceal bleeding. While Blakemore probe tamponade showed high efficacy (80.7%), sclerotherapy had lower success rates (39.8%), suggesting a need for improved patient preparation and staff training.

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Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

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Last Updated: Jul 13, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

Area of Science:

Gastroenterology
Hepatology
Endoscopy

Context:

Esophageal variceal bleeding is a life-threatening complication of portal hypertension.
Emergency endoscopy is the primary diagnostic and therapeutic tool.
Established treatments include endoscopic sclerotherapy (EST), esophageal band ligation (EVL), pharmacotherapy (somatostatin), and balloon tamponade.

Purpose:

To retrospectively analyze the efficacy of different emergency endoscopic interventions for bleeding esophageal varices.
To evaluate the success rates of sclerotherapy, balloon tamponade, and pharmacotherapy in achieving hemostasis.

Summary:

A total of 3,954 emergency upper endoscopies were performed, identifying 324 cases (8.2%) of esophageal variceal bleeding.
Blakemore probe tamponade achieved hemostasis in 80.7% of patients (117/145).
Sclerotherapy with absolute alcohol had a lower success rate, achieving hemostasis in 39.8% of patients (47/118).
Somatostatin analogs were used as primary therapy in 71 patients, with 63.4% achieving hemostasis for 72 hours, and as adjunctive therapy in 169 patients.

Impact:

The study highlights a significantly lower efficacy of sclerotherapy compared to current literature, suggesting potential areas for improvement.
Results indicate a need for enhanced patient preparation and specialized personnel training for endoscopic interventions.
Effective management of esophageal variceal bleeding is critical for reducing mortality and preventing recurrent bleeding.