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Updated: Jul 13, 2026

An Immunofluorescent Method for Characterization of Barrett’s Esophagus Cells
Published on: July 20, 2014
[Expresion of E-cadherin and catenins in urothelial carcinomas]
P San Miguel Fraile1, C Gómez de María, L Donis Quintairos
1Servicio de Anatomía Patológica, Hospital POVISA, Vigo, Pontevedra. psanmiguel@povisa.es
Objective:
We examined the presence of E-cadherin and alpha, beta and gamma catenins detected by immunohistochemistry and correlated with the classic variables: grade, stage and recurrence.
Material And Method:
The authors evaluated 37 transitional cell carcinomas. Biopsy specimens included no recurrent transitional cell carcinoma (n=19) and recurrent transitional cell carcinoma (n=18). Association of E-cadherin and alpha, beta and gamma catenins immunoreactivity with tumor grade, clinical stage and tumor recurrence was examined.
Results:
E-cadherin and gamma catenin expression were related to the clinical stage of the disease, alpha and beta catenins were not correlated with grade, stage and recurrence of disease.
Conclusions:
Decreased E cadherin and gamma catenin expression were associated with advanced stage of the disease.
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