Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 13, 2026

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity
06:46

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

Temporal patterning of saccadic eye movement signals.

Daniel L Kimmel1, Tirin Moore

  • 1Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA. dkimmel@stanford.edu

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|July 20, 2007
PubMed
Summary

Electrical microstimulation patterns significantly impact evoked eye movements. Accelerating pulse patterns, mimicking natural neural activity, are most effective for evoking saccades in experimental neurophysiology and clinical applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A modular neural circuit for computing the motion of objects.

bioRxiv : the preprint server for biology·2026
Same author

Condition-Dependent Noise Correlations without Condition-Dependent Spike Counts.

bioRxiv : the preprint server for biology·2026
Same author

Neuropixels reveal laminar microcircuit organization in monkey V1 in vivo.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Live Spike Sorting of Large-scale Neural Recordings.

bioRxiv : the preprint server for biology·2026
Same author

Ensemble Coding of Hidden Objects in Visual Cortex.

bioRxiv : the preprint server for biology·2026
Same author

Dependence of contextual modulation in macaque V1 on interlaminar signal flow.

eLife·2026

Area of Science:

  • Neuroscience
  • Computational Neuroscience

Background:

  • Electrical microstimulation is a key tool in neurophysiology and clinical neurology.
  • Standard microstimulation uses fixed, equally spaced pulses, which differ from natural neural firing patterns.

Purpose of the Study:

  • To investigate how variable microstimulation pulse patterns affect neural circuit responses.
  • To compare the efficacy of fixed, decelerating, accelerating, and random pulse patterns in evoking eye movements.

Main Methods:

  • Compared microstimulation patterns (fixed, decelerating, accelerating, random) on monkey frontal eye fields.
  • Held mean inter-pulse interval constant across all tested patterns.
  • Analyzed saccade (eye movement) probability and metrics.

Main Results:

More Related Videos

Eye Tracking Young Children with Autism
09:03

Eye Tracking Young Children with Autism

Published on: March 27, 2012

Related Experiment Videos

Last Updated: Jul 13, 2026

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity
06:46

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

Eye Tracking Young Children with Autism
09:03

Eye Tracking Young Children with Autism

Published on: March 27, 2012

  • Microstimulation pulse pattern significantly influences saccade probability and metrics.
  • Accelerating patterns, resembling physiological spike trains, were most effective in evoking saccades.
  • Efficacy correlated positively with the accelerating rate of stimulation.

Conclusions:

  • The temporal pattern of electrical microstimulation critically affects neural responses.
  • Findings have implications for optimizing experimental and clinical microstimulation techniques.
  • Suggests temporal coding in neural circuits can be studied using patterned microstimulation.