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Updated: Jul 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Hospital volume and stroke outcome: does it matter?
G Saposnik1, A Baibergenova, M O'Donnell
1Stroke Program, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, London, ON, Canada. saposnikg@smh.toronto.on.ca
Higher annual hospital stroke admission volumes are linked to reduced patient mortality. This study highlights the importance of hospital volume in stroke care outcomes.
Area of Science:
- Neurology
- Public Health
- Health Services Research
Background:
- Limited understanding of the relationship between annual stroke admission volumes and stroke mortality.
- Previous research explored hospital-outcome relationships for various procedures but not specifically for stroke volume.
Purpose of the Study:
- To investigate the association between facility type, hospital stroke admission volume, and stroke mortality.
- To determine if higher hospital volumes correlate with better stroke patient outcomes.
Main Methods:
- Analysis of ischemic stroke admissions from Canada's national Hospital Morbidity database (HMDB) (April 2003-March 2004).
- Ischemic stroke identified using International Classification of Diseases (ICD-9 and ICD-10) principal diagnosis.
- Multivariable generalized estimating equations used to adjust for demographic factors, provider specialty, facility type, and hospital volume.
Main Results:
- 26,676 ischemic stroke admissions across 606 hospitals were analyzed.
- Seven-day mortality was 7.6%; discharge mortality was 15.6%.
- Patients in high-volume facilities (>100-200 strokes/year) had significantly lower 7-day and discharge mortality compared to low-volume facilities (<50 strokes/year), even after multivariable adjustment.
Conclusions:
- Higher annual hospital stroke volumes are consistently associated with lower stroke mortality.
- Further research is recommended to explore reasons for this association, such as case mix, care organization, or process differences.
- Findings suggest potential benefits of centralizing stroke care in high-volume centers.
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