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Pulmonary and cardiac involvement in Behçet disease: 3 case reports

Zeynep Ilerisoy Yakut1, Kemal Odev

  • 1Department of Radiology, Fatih University Medical School, Ankara, Turkey. drilerisoy@gmail.com

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|July 20, 2007
PubMed

Insights

Behçet disease rarely affects the lungs and heart, leading to serious complications. Advanced imaging like CT and MRI angiography can detect vascular issues, offering a safer alternative to traditional angiography.

Area of Science:

  • Cardiovascular Imaging
  • Rheumatology
  • Pulmonology

Background:

  • Behçet disease is a rare multisystem inflammatory disorder.
  • Pulmonary and cardiac involvement, though infrequent, can be life-threatening.
  • Vascular complications are a significant concern in Behçet disease.

Purpose of the Study:

  • To present imaging findings in three patients with Behçet disease.
  • To highlight the utility of computed tomography and magnetic resonance angiography.
  • To discuss the association of pulmonary vascular disease with cardiac complications.

Main Methods:

  • Retrospective review of three patients with Behçet disease.
  • Computed tomography angiography (CTA) and magnetic resonance angiography (MRA) were utilized.
  • Surgical and conventional angiography findings were used for confirmation.

Main Results:

  • One patient presented with bilateral pulmonary artery aneurysms, one ruptured and thrombosed.
  • Another patient had unilateral pulmonary artery aneurysm with thrombosis and intracardiac thrombus.
  • The third patient exhibited unilateral pulmonary artery aneurysm, thrombus, and coronary artery aneurysm.

Conclusions:

  • Noninvasive imaging modalities like CTA and MRA are valuable for assessing pulmonary and cardiac involvement in Behçet disease.
  • These methods offer a safer alternative to conventional angiography, minimizing endothelial damage.
  • Early detection and management of vascular complications are crucial for improving patient outcomes.

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