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Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
WITHDRAWN: Iron supplementation in pregnancy.
1Ipswich Hospital, Ipswich, Queensland, Australia, 4305. kassam_mahomed@health.qld.gov.au
The Cochrane Database of Systematic Reviews
|July 20, 2007
Summary
Iron supplementation effectively prevents low hemoglobin in pregnant women. However, it shows no clear impact on maternal or fetal outcomes, with limited data in high-risk populations.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Public Health
Background:
- Anemia in pregnancy is a significant global health issue, particularly in developing nations.
- It is linked to nutritional deficiencies, malaria, and parasitic infections, increasing maternal and perinatal risks.
Purpose of the Study:
- To evaluate the impact of iron supplementation on pregnant women's hematological and biochemical markers.
- To assess the effects of iron supplementation on pregnancy outcomes.
Main Methods:
- A systematic review of controlled trials on iron supplementation in pregnancy.
- Data extraction and quality assessment were performed by a single reviewer, with author contact for additional information.
Main Results:
- Iron supplementation increased serum ferritin levels and significantly reduced anemia in late pregnancy.
- No discernible effects were observed on substantive maternal or fetal outcomes.
- One trial indicated increased C-section and transfusion rates but lower perinatal mortality.
Conclusions:
- Iron supplementation appears effective in preventing low hemoglobin levels post-birth.
- There is insufficient evidence regarding the impact on maternal and fetal outcomes.
- More research is needed in populations with high iron deficiency and anemia prevalence.
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