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Related Concept Videos

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Diagnostic studies
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Related Experiment Video

Updated: Jul 13, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
03:19

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes

Published on: June 28, 2024

WITHDRAWN: Nutritional advice in pregnancy.

M S Kramer1

  • 1McGill University, Faculty of Medicine, 1020 Pine Avenue West, Montreal, Quebec, Canada H3A 1A2. michael.kramer@mcgill.ca

The Cochrane Database of Systematic Reviews
|July 20, 2007
PubMed
Summary

Nutritional advice can increase pregnant women's energy and protein intake, but its impact on pregnancy outcomes remains unclear. The benefits appear modest compared to direct supplementation.

Area of Science:

  • Obstetrics and Gynecology
  • Nutritional Science
  • Public Health

Background:

  • Nutritional status during pregnancy is crucial for maternal and fetal well-being.
  • Previous research has explored the effects of nutritional supplementation.
  • The impact of specific nutritional advice on pregnancy outcomes requires further investigation.

Purpose of the Study:

  • To evaluate the effectiveness of advising pregnant women to increase energy and protein intake.
  • To assess the impact of this advice on maternal nutritional status and gestational weight gain.
  • To determine the influence of nutritional advice on pregnancy outcomes.

Main Methods:

  • Systematic review of controlled clinical trials.
  • Included trials involved nutritional advice on energy and protein intake.

Related Experiment Videos

Last Updated: Jul 13, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
03:19

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes

Published on: June 28, 2024

  • Data extracted from published reports and direct contact with trialists.

    • Main Results:

    • Nutritional advice successfully increased energy and protein intake, though less than direct supplementation.
    • Limited data on pregnancy outcomes; one trial's analysis had narrow confidence intervals.
    • No consistent evidence of reduced preterm birth, pre-eclampsia, or improved gestational age.

    Conclusions:

    • Nutritional advice effectively increases pregnant women's energy and protein intake.
    • Available trial data are insufficient to determine implications for maternal or infant health.
    • The overall importance of such advice is likely minor, given modest benefits of supplementation.