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WITHDRAWN: Interventions for chronic suppurative otitis media.

J Acuin1, A Smith, I Mackenzie

  • 1De La Salle University, Health Sciences Campus, Clinical Epidemiology Unit, Cong. Road, Dasmariñas, Cavite 4114, Philippines. jmacuin@pworld.net.ph

The Cochrane Database of Systematic Reviews
|July 20, 2007
PubMed
Summary
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Topical antibiotics, especially quinolones, combined with aural toilet effectively treat chronic suppurative otitis media (CSOM) by resolving ear discharge. Further research is needed on long-term outcomes for CSOM patients.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Pharmacology

Background:

  • Chronic suppurative otitis media (CSOM) is a significant middle ear bacterial infection.
  • CSOM can develop from inadequately treated acute otitis media.

Purpose of the Study:

  • To evaluate the efficacy of various treatments for CSOM.
  • To compare different therapeutic approaches for managing persistent otorrhea in patients with eardrum perforation.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) published between 1966 and 1996.
  • Searched multiple databases and contacted experts to identify relevant studies.
  • Included 24 RCTs involving 1660 participants, assessing treatment for CSOM.

Main Results:

Related Experiment Videos

  • Aural toilet with antibiotics or antiseptics was more effective than no treatment or aural toilet alone in resolving otorrhea.
  • Topical treatments (antibiotics/antiseptics) outperformed systemic antibiotics.
  • Topical quinolone antibiotics demonstrated superior efficacy compared to non-quinolone topical agents in resolving otorrhea.

Conclusions:

  • Aural toilet and topical antibiotics, particularly quinolones, are effective for CSOM symptom resolution and bacterial eradication.
  • Long-term efficacy, including recurrence prevention, tympanic membrane healing, and hearing improvement, requires further investigation.