Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methods of determining bone mass.

S M Ott1

  • 1Department of Medicine, University of Washington, Seattle.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atypical femur fracture incidence in women increases with duration of bisphosphonate exposure.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2019
Same author

Sensitivity and specificity of radiographic characteristics in atypical femoral fractures.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
Same author

Utility of automated data in identifying femoral shaft and subtrochanteric (diaphyseal) fractures.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2010
Same author

Bisphosphonates and BMU birth rate.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2009
Same author

Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2008
Same author

Association between caffeine intake and bone mass among young women: potential effect modification by depot medroxyprogesterone acetate use.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2007

Primary hyperparathyroidism causes non-uniform bone loss, affecting wrists and cortical bone more than the spine. Understanding bone composition at measurement sites is crucial for accurate assessment of bone disease.

Area of Science:

  • Endocrinology
  • Bone Metabolism
  • Radiology

Background:

  • Primary hyperparathyroidism is a common cause of bone disease.
  • Bone loss in primary hyperparathyroidism is not uniform across the skeleton.
  • Cortical bone and wrist regions show greater bone loss compared to spinal and iliac crest trabecular bone.

Purpose of the Study:

  • To highlight the importance of understanding trabecular bone percentage at various skeletal sites for accurate assessment of bone disease in primary hyperparathyroidism.
  • To emphasize the need for precise measurement techniques and understanding measurement error in evaluating bone mass changes.
  • To call for further research into bone loss patterns and fracture risk in hyperparathyroidism.

Main Methods:

  • Review of existing studies on bone loss patterns in primary hyperparathyroidism.

Related Experiment Videos

  • Discussion of trabecular bone percentages at key skeletal sites (distal radius, midradius, vertebrae, vertebral body, femoral neck).
  • Explanation of measurement precision and its impact on detecting real changes in bone mass.

    • Main Results:

    • Bone loss is site-specific, with greater loss in cortical bone and peripheral sites like the wrist.
    • Trabecular bone percentages vary significantly across different skeletal sites.
    • Dual-energy x-ray absorptiometry offers the best precision among available noninvasive bone mass measurement techniques.

    Conclusions:

    • Accurate assessment of bone disease in primary hyperparathyroidism requires consideration of site-specific bone composition.
    • Further longitudinal studies are needed to fully characterize bone loss patterns and fracture risks.
    • Noninvasive bone densitometry techniques, particularly dual-energy x-ray absorptiometry, are essential tools for monitoring bone health.