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Updated: Jul 11, 2026

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
Published on: December 14, 2015
Model of the reception of hedgehog morphogen concentration gradient: comparison with an extended range of
Konstantin V Gunbin1, Leonid V Omelyanchuk, Vladislav V Kogai
1Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, 10 Acad. Lavrent'ev Ave., Novosibirsk, 630090, Russia. genkvg@bionet.nsc.ru
Abstract:
The model for reception of the concentration gradient of the Hedgehog morphogen has been developed. The mechanism of co-operation of the proteins Patched, Smoothened, and Hedgehog is theoretically analyzed in terms of different versions of interactions within this group of proteins. The parametric stability of the modeled system is considered.
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