Related Experiment Video
Updated: Jul 13, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Pericardial tamponade presenting as abdominal pain in a patient with systemic lupus erythematosis
1Department of Emergency Medicine and Pediatrics, Medical College of Virginia, Richmond, Virginia, USA. aemuniz@aol.com
Insights
Abdominal pain in children with systemic lupus erythematosus (SLE) can mask serious conditions like cardiac tamponade. Early diagnosis is crucial, as SLE complications can be life-threatening.
Area of Science:
- Pediatric Rheumatology
- Pediatric Emergency Medicine
- Cardiology
Background:
- Abdominal pain is a frequent emergency department complaint in children.
- Systemic lupus erythematosus (SLE) patients face heightened risks of gastrointestinal complications, including infection, necrosis, and perforation.
- Medications like NSAIDs, corticosteroids, and immunosuppressants can obscure SLE symptoms, delaying critical diagnosis and treatment.
Purpose of the Study:
- To highlight a case of abdominal pain in an adolescent with SLE due to cardiac tamponade.
- To review cardiac and gastrointestinal manifestations of SLE in pediatric patients.
Main Methods:
- Case report presentation.
- Literature review of cardiac and gastrointestinal manifestations in SLE.
Main Results:
- An adolescent female presented with abdominal pain attributed to cardiac tamponade, a rare but serious SLE complication.
- The case underscores the diverse and potentially severe presentations of SLE in children.
Conclusions:
- Abdominal pain in pediatric SLE requires thorough investigation beyond typical gastrointestinal causes.
- Cardiac tamponade is a critical differential diagnosis in SLE patients with abdominal pain.
- Recognizing both cardiac and GI manifestations is vital for timely management of pediatric SLE.
Abstract:
Abdominal pain is a common complaint in children presenting to the emergency department. Patients with systemic lupus erythematosus (SLE) are at increased risk of infection, bowel necrosis and perforation, especially if they are taking nonsteroidal anti-inflammatory drugs, corticosteroids or immunosuppresive agents, which may mask the signs and symptoms of the underlying condition, hence delay diagnosis and treatment. This article presents the case of an adolescent girl whose abdominal pain was related to cardiac tamponade and provides an overview of the cardiac and gastrointestinal manifestations of SLE.
Related Concept Videos
Pericarditis II: Clinical Features and Diagnostic Tests
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Pericarditis IV: Nursing Management
Pericarditis III: Medical Management
Pericarditis I: Introduction
Rheumatic Heart Disease I: Introduction