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Polyamine-modulated factor 1 represses glucocorticoid receptor activity.

Yutaka Shoji1, Waffa Osman, Johanna Zilliacus

  • 1Department of Biosciences and Nutrition, Karolinska Institutet, Novum, SE-141 86 Huddinge, Sweden.

Biochemical and Biophysical Research Communications
|July 20, 2007
PubMed
Summary

Polyamine-modulated factor 1 (PMF-1) binds to the glucocorticoid receptor (GR) and represses its activity. This finding reveals a new role for PMF-1 in regulating gene expression and cellular responses to glucocorticoids.

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