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Published on: March 8, 2018
Psychotic symptoms in posttraumatic stress disorder
S E Lindley1, E Carlson, J Sheikh
1National Center for PTSD, Palo Alto VA Health Care System, Menlo Park, CA, USA.
Psychotic symptoms in posttraumatic stress disorder (PTSD) may indicate a unique subtype. This subtype is linked to severe psychopathology, requiring differential diagnosis and further research in diverse populations.
Area of Science:
- Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Posttraumatic stress disorder (PTSD) is increasingly recognized to present with psychotic symptoms.
- Approximately 30-40% of combat veterans with PTSD report hallucinations or delusions.
- Psychotic symptoms in PTSD are associated with elevated psychopathology, comparable to chronic schizophrenia.
Purpose of the Study:
- To review the differential diagnosis of psychotic symptoms in PTSD.
- To explore the potential for a unique PTSD subtype with psychotic features.
- To examine treatment implications for PTSD with psychotic features.
Main Methods:
- Literature review of studies on psychotic symptoms in PTSD.
- Discussion of differential diagnoses including schizophrenia, psychotic depression, substance-induced psychosis, and personality disorders.
- Analysis of biologic studies and treatment data.
Main Results:
- Psychotic symptoms in PTSD suggest a distinct subtype with severe psychopathology.
- Differential diagnosis is crucial to distinguish from comorbid conditions.
- Similarities exist between PTSD with psychotic features and psychotic depression.
Conclusions:
- PTSD with psychotic features may represent an underrecognized subtype.
- Further research is needed in noncombat-related PTSD populations.
- Understanding this subtype has significant diagnostic and treatment implications.
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