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New lipoxygenase-inhibiting constituents from Calligonum polygonoides
Mirza Arfan Yawer1, Ejaz Ahmed, Abdul Malik
1International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Chemistry & Biodiversity
|July 20, 2007
Abstract:
Calligonolides A (1) and B (2), two new butanolides, and a new steroidal ester, 3, have been isolated from the whole plant of Calligonum polygonoides, together with four known compounds, tetracosan-4-olide, beta-sitosterol and its glucoside, and ursolic acid. Their structures were elucidated by spectroscopic and mass-spectrometric studies. Compounds 1-3 showed moderate inhibitory potential against lipoxygenase from soybean.