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Related Experiment Video

Updated: Jul 13, 2026

Single Port Donor Nephrectomy

Single Port Donor Nephrectomy

Published on: March 12, 2011

Rapid communication: transvaginal single-port NOTES nephrectomy: initial laboratory experience.

Ralph V Clayman¹, Geoffrey N Box, Jose Benito A Abraham

¹Department of Urology, Division of Gastroenterology, University of California, Irvine, Orange, California 92868, USA. rclayman@uci.edu

Journal of Endourology

|July 20, 2007

Summary

Transvaginal natural orifice translumenal endoscopic surgery (NOTES) nephrectomy was successfully performed in a porcine model. This novel approach utilized a single port for kidney removal, demonstrating feasibility for future urologic applications.

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Area of Science:

Urologic Surgery
Minimally Invasive Surgery
Natural Orifice Translumenal Endoscopic Surgery (NOTES)

Background:

Natural orifice translumenal endoscopic surgery (NOTES) has not been previously applied to urologic procedures.
This study introduces the first experience with transvaginal NOTES nephrectomy.

Purpose of the Study:

To evaluate the feasibility of a transvaginal single-port NOTES nephrectomy.
To demonstrate the application of purpose-built equipment in urologic NOTES.

Main Methods:

An acute experiment was conducted in a female farm pig.
A single 12-mm trocar was used for transvaginal access, accommodating the TransPort Multi-Lumen Operating Platform.
The procedure involved endoscopic dissection, vascularTransaction, and intact kidney retrieval via the vagina.

Main Results:

The transvaginal NOTES nephrectomy was successfully completed in the porcine model.
The total operative time was 300 minutes.
The kidney was retrieved intact through the vaginal route.

Conclusions:

Transvaginal NOTES nephrectomy is achievable in a porcine model.
Further studies involving survival animals are required to validate this surgical approach.