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Optimized PCR-based Detection of Mycoplasma
Published on: June 20, 2011
In vitro susceptibilities of Mycoplasma putrefaciens field isolates
N T Antunes1, M M Tavío, P Mercier
1Unidad de Epidemiología y Medicina Preventiva, Instituto Universitario de Sanidad Animal (IUSA), Universidad de Las Palmas de Gran Canaria Trasmontaña s/n, 35416 Arucas, Spain. nuno.giao101@doctorandos.ulpgc.es
Antimicrobial Agents and Chemotherapy
|July 20, 2007
Summary
This study assessed antimicrobial susceptibility in Mycoplasma putrefaciens. Fluoroquinolones, tetracyclines, lincomycin, and macrolides were most effective, with geographic variations noted.
Area of Science:
- Microbiology
- Antimicrobial Resistance
- Veterinary Medicine
Background:
- Mycoplasma putrefaciens is an emerging pathogen.
- Understanding its antimicrobial susceptibility is crucial for effective treatment.
- Limited data exists on the resistance patterns of this bacterium.
Purpose of the Study:
- To determine the minimum inhibitory concentrations (MICs) of various antimicrobial agents against Mycoplasma putrefaciens isolates.
- To identify the most effective antimicrobial classes against this pathogen.
- To investigate potential correlations between geographic origin and susceptibility profiles.
Main Methods:
- MICs were determined for 37 Mycoplasma putrefaciens isolates using 15 antimicrobial agents.
- Standard microbiological techniques were employed for susceptibility testing.
Main Results:
- Fluoroquinolones, tetracyclines, lincomycin (a lincosamide), and macrolides demonstrated the highest efficacy.
- A correlation was observed between the geographic origin of isolates and their antimicrobial susceptibility profiles.
- This study reports the first instances of decreased susceptibility to macrolides, lincomycin, and tetracyclines in M. putrefaciens.
Conclusions:
- Fluoroquinolones, tetracyclines, lincomycin, and macrolides are recommended for treating Mycoplasma putrefaciens infections.
- Geographic factors may influence the antimicrobial resistance patterns of M. putrefaciens.
- Emerging resistance to macrolides, lincomycin, and tetracyclines necessitates ongoing surveillance.
